Endocrine Abstracts

Introduction: The number of patients with diabetes has been increasing at an alarming pace for the last decade. Sexuality is frequently affected in diabetic patients.The aim of this study was to describe the clinical profile of a group of type 2 diabetic patients suffering of erectile dysfunction (ED).Methodology: This was a cross-sectional study involving a population of 70 type 2 diabetic patients recruited from the day hospital ...

Background: Thyroid nodules (TN) are common. Their prevalence increases with age. A thyroid incidentaloma (TI) is defined as a non-palpable TN detected fortuitously during a radiological investigation performed for reasons unrelated to the thyroid gland. Although they are mostly benign, the risk of malignancy is estimated from 7% to 15% of nodules. The objective of this study is to investigate the characteristics of TI in a cohort of patients admitted in an internal medicine d...

Introduction: Retinal vein occlusions (RVO) are a heterogeneous group of disorders characterized by impaired venous return from retinal circulation. RVO can be classified into branch retinal vein occlusion (BRVO), hemiretinal vein occlusion (HRVO), and central retinal vein occlusion (CRVO) depending on the site of the obstruction. Major risk factors for BRVO include systemic arterial hypertension, arteriosclerosis, and diabetes, although many associations have been reported in...

Introduction: 21-hydroxylase deficiency represents 95% of congenital adrenal hyperplasia. The non-classical form manifests in women mainly by hirsutism, menstrual disorders, or infertility. We present three patients’ cases.Observations: Patient N.C., 17 years old, who presented with hirsutism beginning at the age of 8 years and progressively worsening after puberty. The patient had her menarche at the age of 9 years, with short and irregular menses....

Introduction: Uncontrolled hyperglycemia in diabetes is a common cause of microvascular complications, including diabetic nephropathy (DN). Despite improvements in the management of type 2 diabetes (T2DM), diabetic nephropathy is still associated with high morbidity and mortality. The objective of our study is to evaluate the predictive factors of DN in adults with T2DM in order to prevent its development.Patients and Methods: A retrospective study, incl...

Background: Adrenocortical carcinoma is a rare malignancy with a poor prognosis. Local recurrence is affected by the pathologic features (tumor staging and mitotic index) and the complete surgical resection. Treatment of a recurrent adrenocortical carcinoma can be a real challenge.Case description: We report a case of 47-year-old man who was operated for an adrenal tumor with bone metastases. Left adrenalectomy and splenectomy were performed and histolog...

Introduction: Cushing’s disease (CD), a hypercorticism caused by an ACTH-secreting pituitary adenoma, was associated with a 5-year survival of only 50%. Although advances in management have significantly reduced mortality, the results of transsphenoidal surgery, the gold standard in the treatment of CD, vary from patient to patient.Objective: The aim of our study is to evaluate the results of transsphenoidal surgery in CD (evolution, complications) ...

Introduction: It has been generally accepted that adrenal function might be impaired in patients with primary hypothyroidism. A transitory low glucocorticoid production has been identified in cases with severe hypothyroidism. We tried to evaluate adrenocortical glucocorticoid function using the low-dose Synacthen test, in patients with primary hypothyroidism. The primary endpoint was to contrast the cortisol response to low-dose Synacthen before L-T4 replacement and after norm...

Introduction: The management of diabetes goes through the education but also the management of acute and chronic complications. Among the complications, erectile dysfunction are too often forgotten as they actually affect the quality of life. The repercussions of this complication incite the clinician to look for it among the other complications of diabetes. The aim of our study is to evaluate the prevalence of erectile dysfunction in a diabetic population and to evaluate its ...

Introduction: The prevalence of Gestational diabetes mellitus (GDM) has been increasing recently. Educating women of childbearing age about GDM, its risk factors and complications may help its prevention and improve its outcomes. Hence, the aim of this study was to assess the level of knowledge of Tunisian pregnant women about gestational diabetes, its risk factors and its consequences.Methods: We conducted a cross-sectional study among pregnant women wh...